Bone grafts and substitutes are the natural and synthetic products used by the surgeons to repair and reform bones in the spine, hips and knees through a medical procedure known as bone grafting. The bone used during grafting could be natural or synthetic. The most common types of bone grafts used are the autograft and allograft. An autograft comes from patients own body such as hips, pelvis and wrist. Allograft uses bone from deceased donor or a cadaver bone that has been cleaned and stored in the tissue banks. Bone graft substitutes are the synthetic or derived from allografts in varied forms. Synthetic bone grafts are made up of ceramics, composites, and polymer. Bone grafts substitutes are allografts based (Demineralized Bone Matrix), factor based such as transforming growth factor beta (TGF-beta), and platelet derived growth factor (PDGF), fibroblast growth factor (FGF), and bone morphogenetic proteins (BMP) and cell based bone grafts substitutes to generate new tissue alone or placed into support matrix (eg, mesenchymal stem cells). Bone graft and substitutes are primarily used because of fractures, fusion of two bones, bone and tissue regeneration and for bone healing with the implanted devices.
The major factors driving the market are rising incidences of musculoskeletal conditions, increasing base of elderly population and development of biocompatible synthetic bone grafts.
Market Dynamics
Bone grafts and substitutes market witnessed new product launches, partnerships and agreements in last few months. In October, 2017, DSM Biomedical signed a partnership agreement with a privately held orthobiologics company, Cerapedics to develop peptide enhanced bone graft. The strategic partnership will complement DSM’s material regeneration abilities with Cerapedics synthetic small peptide (P-15) technology. In April, 2017, BoneSupport AB extended its U.S distribution agreement with Zimmer Biomet for its Cerament bone void filler product. According to the agreement Zimmer will have exclusive rights to distribute portfolio of bone void fillers for trauma, orthopedics and foot and ankle applications. In May, 2017, NovaBone introduced NovaBone IRM and IRM MacroPOR to its product portfolio. According to NovaBone, the products possess osteogenic and osteoblastic characteristics and are highly irrigation resistant. Increase in awareness of non-invasive technologies among the patients and shift towards derived forms of bone graft substitutes are also expected to favor the market in near future.
Key features of the study:
This report provides an in-depth analysis of global bone graft and substitutes market provides market size (US$ Million) and Cumulative Annual Growth Rate (CAGR %) for the forecast period (2017 – 2025), considering 2016 as the base year.
It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market.
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, regional outlook, and competitive strategy adopted by the leading players.
It profiles leading players in the global bone grafts and substitutes market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments and strategies, and future plans.
Key companies covered as a part of this study include Stryker Corporation, Medtronic Inc., DePuySynthes, Zimmer Biomet Holdings, NuVasive Inc., Orthofix International N.V, Bone Therapeutics, RTI Surgical Inc., Institute Straumann AG and BioHorizons IPH
Insights from this report would allow marketers and the management authorities of the companies to make informed decision regarding their future product launch, technology up-gradation, market expansion, and marketing tactics.
The global bone grafts and substitutes market report caters to various stakeholders in this industry including investors, suppliers, implant devices and consumables manufacturers, distributors, new entrants, and financial analysts.
Stakeholders would have ease in decision making through the various strategy matrices used in analyzing the implant devices and consumables market.
Detailed Segmentation:
Global Bone Graft and Substitutes Market, By Product type:
Bone Grafts
Allograft
Xenograft
Bone Graft Substitutes
Ceramic
Composite
Polymer
Bone Morphogenetic Proteins (BMP)
Demineralized Bone Matrix (DBM)
Others
Global Bone Graft and Substitutes Market, By Application:
Spinal Fusion
Dental
Craniomaxillofacial
Joint Reconstruction
Trauma and Extremities
Global Bone Graft and Substitutes Market, By Geography:
North America
By Product Type:
Bone Grafts
Allograft
Xenograft
Bone Graft Substitutes
Ceramic
Composite
Polymer
Bone Morphogenetic Proteins (BMP)
Demineralized Bone Matrix (DBM)
Others
By Application:
Spinal Fusion
Dental
Craniomaxillofacial
Joint Reconstruction
Trauma and Extremities
By Country
U.S.
Canada
Europe
By Product Type:
Bone Grafts
Allograft
Xenograft
Bone Graft Substitutes
Ceramic
Composite
Polymer
Bone Morphogenetic Proteins (BMP)
Demineralized Bone Matrix (DBM)
Others
By Application:
Spinal Fusion
Dental
Craniomaxillofacial
Joint Reconstruction
Trauma and Extremities
By Country
U.K.
Germany
Italy
France
Russia
Rest of Europe
Asia Pacific
By Product Type:
Bone Grafts
Allograft
Xenograft
Bone Graft Substitutes
Ceramic
Composite
Polymer
Bone Morphogenetic Proteins (BMP)
Demineralized Bone Matrix (DBM)
Others
By Application:
Spinal Fusion
Dent
Craniomaxillofacial
Joint Reconstruction
Trauma and Extremities
By Country
China
India
Japan
ASEAN
Australia
South Korea
Rest of Asia Pacific
Latin America
By Product Type:
Bone Grafts
Allograft
Xenograft
Bone Graft Substitutes
Ceramic
Composite
Polymer
Bone Morphogenetic Proteins (BMP)
Demineralized Bone Matrix (DBM)
Others
By Application:
Spinal Fusion
Dental
Craniomaxillofacial
Joint Reconstruction
Trauma and Extremities
By Country
Brazil
Mexico
Rest of Latin America
Middle East
By Product Type:
Bone Grafts
Allograft
Xenograft
Bone Graft Substitutes
Ceramic
Composite
Polymer
Bone Morphogenetic Proteins (BMP)
Demineralized Bone Matrix (DBM)
Others
By Application:
Spinal Fusion
Dental
Craniomaxillofacial
Joint Reconstruction
Trauma and Extremities
By Country
GCC
Israel
Rest of Middle East
Africa
By Product Type:
Bone Grafts
Allograft
Xenograft
Bone Graft Substitutes
Ceramic
Composite
Polymer
Bone Morphogenetic Proteins (BMP)
Demineralized Bone Matrix (DBM)
Others
By Application:
Spinal Fusion
Dental
Craniomaxillofacial
Joint Reconstruction
Trauma and Extremities
By Country
North Africa
Central Africa
South Africa
Company Profiles
Stryker Corporation*
Company Overview
Product Portfolio
Financial Performance
Key Strategies
Recent Developments
Zimmer Biomet Holdings
Orthofix International N.V
Medtronic, Inc.
DePuySynthes
RTI Surgical Inc.
Bone Therapeutics
Institute Straumann AG
NuVasive Inc.
“*” marked represents similar segmentation in other categories in the respective section.
Table of Contents
1. Research Objective and assumption
o Research Objectives
o Assumptions
o Abbreviations
2. Market Purview
o Report Description
? Market Definition and Scope
o Executive Summary
? Market Snippet By Product Type
? Market Snippet By Application
? Market Snippet By Region
o Coherent Opportunity Map (COM)
3. Market Dynamics, Regulations, and Trends Analysis
o Market Dynamics
? Drivers
? Restraints
? Market Opportunities
o Regulatory Scenario
o Industry Trend
o Merger and Acquisitions
o New Product Approvals/Launch
o Promotion and Marketing Initiatives
4. Global Bone Graft and Substitutes Market, By Product type, 2015 - 2025 (US$ Million)
o Introduction
? Market Share Analysis, 2016 and 2025 (%)
? Y-O-Y Growth Analysis, 2015 - 2025
? Segment Trends
o Bone Grafts
? Introduction
? Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
? Allograft
• Introduction
• Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
? Xenograft
• Introduction
• Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
o Bone Graft Substitutes
? Introduction
? Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
? Ceramic
• Introduction
• Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
? Composite
• Introduction
• Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
? Polymer
• Introduction
• Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
? Bone Morphogenetic Proteins (BMP)
• Introduction
• Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
? Demineralized Bone Matrix (DBM)
• Introduction
• Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
? Others
• Introduction
• Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
5. Global Bone Graft and Substitutes Market, By Application, 2015 - 2025 (US$ Million)
o Introduction
? Market Share Analysis, 2016 and 2025 (%)
? Y-O-Y Growth Analysis, 2015 - 2025
? Segment Trends
o Spinal Fusion
? Introduction
? Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
o Dental
? Introduction
? Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
o Craniomaxillofacial
? Introduction
? Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
o Joint Reconstruction
? Introduction
? Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
o Trauma and Extremities
? Introduction
? Market Size and Forecast, and Y-O-Y Growth, 2015 - 2025, (US$ Million)
6. Global Bone Graft and Substitutes, By Regions, 2015 - 2025 (US$ Million)
o Introduction
? Market Share Analysis, By Region, 2016 and 2025 (%)
? Y-o-Y Growth Analysis, For Regions, 2015 - 2025
? Regional Trends
o North America
? Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Application, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
? U.S.
? Canada
o Europe
? Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Application, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
? Germany
? U.K.
? France
? Italy
? Spain
? Russia
? Rest of Europe
o Asia Pacific
? Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Application, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
? China
? India
? Japan
? Australia
? South Korea
? ASEAN
? Rest of APAC
o Latin America
? Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Application, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
? Brazil
? Mexico
? Rest of Latin America
o Middle East
? Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Application, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
? GCC
? Israel
? Rest of Middle East
o Africa
? Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Application, 2015 - 2025 (US$ Mn)
? Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
? South Africa
? North Africa
? Central Africa
7. Competitive Landscape
o Heat Map Analysis
o Company Profiles
? Medtronic plc
? Company Overview
? Product Portfolio
? Financial Performance
? Recent Developments/Updates
? Future Plans
? RTI Surgical, Inc.
? Company Overview
? Product Portfolio
? Financial Performance
? Recent Developments/Updates
? Future Plans
? Stryker Corporation
? Company Overview
? Product Portfolio
? Financial Performance
? Recent Developments/Updates
? Future Plans
? Zimmer Biomet Holdings
? Company Overview
? Product Portfolio
? Financial Performance
? Recent Developments/Updates
? Future Plans
? Orthofix International N.V.
? Company Overview
? Product Portfolio
? Financial Performance
? Recent Developments/Updates
? Future Plans
? DePuySynthes
? Company Overview
? Product Portfolio
? Financial Performance
? Recent Developments/Updates
? Future Plans
? Bone Therapeutics
? Company Overview
? Product Portfolio
? Financial Performance
? Recent Developments/Updates
? Future Plans
? NuVasive Inc.
? Company Overview
? Product Portfolio
? Financial Performance
? Recent Developments/Updates
? Future Plans
? Institute Straumann AG
? Company Overview
? Product Portfolio
? Financial Performance
? Recent Developments/Updates
? Future Plans
o Analyst Views
8. Section
o References
o Research Methodology
o About us and Sales Contact
*Browse 29 market data tables and 37 figures on "Global Bone Grafts and Substitutes Market" - Global forecast to 2025".
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